Fabrication, packaging, and application of micromachined hollow polymer needle arrays

Micromachined needles (MN) have been shown to successfully transport biological molecules into the body with minimal invasiveness and pain, following the insertion of needles into the skin. The aim of this research is to demonstrate that micromachined hollow polymer needle arrays fabricated using UV lithography into micromolds can exhibit comparable insertion and injection performance to conventional hypodermic needles for drug delivery into skin. The literature on both solid and hollow microneedles is reviewed in Chapter 2 to provide a complete overview of the microfabrication and packaging involved in the MN researches (Georgia Institute of Technology, 11 November 2013).
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