Effects of the exposure to an organomodified clay mineral for food packaging applications on rats

Organomodified clay minerals have many applications, but there are in vitro toxicological studies that have shown adverse effects induced by organomodified clay minerals in human cell lines. However, in vivo toxicity reports are scarce, particularly those using the oral pathway.
Researchers at the University of Seville in Spain evaluated the toxicity of an organomodified clay mineral, Clay1. A repeated dose 90-day oral toxicity study was performed in Wistar rats exposed to 40 mg/kg/day Clay1. The results suggest that Clay1 does not cause remarkable toxic effects at the conditions tested. An article about the research is published in Applied Clay Science.
Click here for an abstract of the article.

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