Plastic vs. glass: less aluminium in parenteral solutions

The primary aluminium source among parenteral nutrition components is glass-packaged calcium gluconate, in which aluminium concentration the past three decades has averaged~ 4000 [mu]g/L, compared to < 200 [mu]g/L in plastic container-packaged calcium gluconate. A concern about plastic packaging is leaching of plasticizers, including phthalates, which have the potential to cause endocrine (male reproductive system) disruption and neurotoxicity. The researchers conclude that plastic packaging greatly reduces the contribution of aluminium to parenteral nutrition solutions from calcium gluconate compared to the glass-packaged product. An article about the research was published in the JPGN.
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